Role of CFTR in lysosome acidification
نویسندگان
چکیده
منابع مشابه
Role of CFTR in lysosome acidification.
The role of CFTR in lysosome acidification was examined in CFPAC-1 pancreatic adenocarcinoma cells with the delta F508 mutation that were transduced with a retroviral vector (PLJ-CFPAC) or with the normal CFTR gene (CFTR-CFPAC). Steady-state lysosomal pHi in intact cells was lower in PLJ-CFPAC cells than CFTR-CFPAC cells (3.55 vs 3.80) and was not affected by cAMP or forskolin. Initial rates of...
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ژورنال
عنوان ژورنال: Biochemical and Biophysical Research Communications
سال: 1992
ISSN: 0006-291X
DOI: 10.1016/0006-291x(92)91192-s